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Repligen Corporation (Nasdaq: RGEN) announced that based on feedback from the Food and Drug Administration, the Company plans to initiate a Phase 2b clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar disorder later this year. This will be a multi-center, parallel arm placebo-controlled, clinical trial in which approximately 150 patients with bipolar disorder will receive either RG2417 or a placebo twice a day for eight-weeks.
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Patients with pain caused by narrowed arteries in their legs have 37% more pain-free walking if they take naftidrofuryl (200mg three times a day) than those taking placebos, a Cochrane Review has found. In addition, 55% of patients taking naftidrofuryl improved, while only 30% of people on placebo treatments improved. Naftidrofuryl is used to treat circulatory problems.
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National charity for people with learning disabilities, HFT, has teamed up with charity and voluntary agency, Onside Independent Advocacy, to launch a new initiative which will enhance support for people with profound and multiple learning disabilities.
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