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The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors.
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The American Association of Kidney Patients (AAKP) is pleased to announce the availability of its updated Advisory on Peritoneal Dialysis (PD). This brochure is part of AAKP's "Advisory" series which provides information on the importance of adequate dialysis. The Advisory on Peritoneal Dialysis helps patients understand how PD adequacy is measured.
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Seeking to improve on nature, scientists used a spice-based compound as a starting point and developed synthetic molecules that, in lab settings, are able to kill cancer cells and stop the cells from spreading. The researchers are combining organic chemistry, computer-aided design and molecular biology techniques in developing and testing pharmaceutical compounds that can fight breast and prostate cancer cells.
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July 19, 2008, 15:57
July 21, 2008, 06:42 1. Wnt Effects on Growth Cone Microtubules Silvia A. Purro, Lorenza Ciani, Monica Hoyos-Flight, Eleanna Stamatakou, Eliza Siomou, and Patricia C. Salinas Wnt family proteins are secreted from target tissues and regulate axonal terminal arborization during development. In the canonical Wnt pathway, Wnt signals through the phosphoprotein Dishevelled, which leads to inhibition of the kinase Gsk3, elevation of β-catenin, and activation of transcription. Purro et al.
July 23, 2008, 12:05
July 23, 2008, 20:54 1. Wnt Effects on Growth Cone Microtubules Silvia A. Purro, Lorenza Ciani, Monica Hoyos-Flight, Eleanna Stamatakou, Eliza Siomou, and Patricia C. Salinas Wnt family proteins are secreted from target tissues and regulate axonal terminal arborization during development. In the canonical Wnt pathway, Wnt signals through the phosphoprotein Dishevelled, which leads to inhibition of the kinase Gsk3, elevation of β-catenin, and activation of transcription. Purro et al.